What can indiscriminate use of high-level fluoroscopy cause?

The indiscriminate use of high-level fluoroscopy can lead to radiation damage to underlying tissues due to the increased exposure of patients to ionizing radiation. Fluoroscopy is a real-time imaging technique that allows for the visualization of internal structures, but when not managed properly, particularly with high-dose protocols, it can pose significant risks.

Such radiation effects can range from transient skin reactions, such as erythema or burns, to more severe and long-term consequences including tissue necrosis and an increased risk of cancer. The cumulative effects of this radiation exposure can lead to substantial biological damage even after a single excessive session. It is vital in clinical practice to adhere to the principle of ALARA (As Low As Reasonably Achievable), which emphasizes minimizing radiation exposure while still achieving necessary diagnostic or therapeutic results.

The other options relate to different aspects of patient care or imaging physics that do not directly involve the adverse effects of radiation from fluoroscopy. Decreased patient comfort and skin cooling are more about procedural patient management, while increased signal-to-noise ratio pertains to the technical aspects of imaging quality rather than the health risks associated with excessive radiation exposure.